Barbecued Beef

1 1/2 cups ketchup 1/4 cups packed brown sugar 1/4 cup red wine vinegar 2 tablespoons mustard 2 tablespoons Worcestershire sauce 1 teaspoon liquid smoke 1/2 teaspoon salt 1/4 teaspoon ground black pepper 1/4 teaspoon garlic powder 1 (4 pound) boneless chuck roast 1. In a large owl, combine ketchup, brown sugar, red wine vinegar, mustard, Worcestershire sauce, liquid smoke, salt, pepper, and garlic powder. 2. Place chuck roast in a slow cooker. Pour ketchup mixture over chuck roast. Cover and cook on low for 8 to 10 hours. 3. Remove chuck roast from slow cooker, shred with a fork and return to the slow cooker. Stir meat to evenly coat with sauce. Continue cooking approximately 1 hour.